| (Succinimidyl-3-(2-pyridyldithio)propionate) as a heterobifunctional reagent, MW:312.4; Spacer arm:6.6 angstroms; Purity:>95% on TLC; introduces thiol groups into a variety of proteins; Reactive groups:primary amine and sulfhydryl reactive. Cleavable treatment with DTT releases 2-pyridylthione and a mercaptopropionyl modified amine. Ref:Cumber, J.,A., et al., Methods Enzymology, 112, 207-224 (1985). Gordon, R.D., et al., PNAS, 84, 308-312 (1987). Carlsson, J. et al., J. Biochem., 173, 723-737 (1978). |
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