his gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6
Properties
IHC Recommended dulition
25-50
IHC positive control
Human cervical and thyroid cancer
IHC predicted cell location
Cytoplasm
WB Exposure time
10 seconds
WB Primary antibody actual dilution
500
WB Lysates(ug)
30
Gel concentration
8
WB Recommended dilution
500-1000
WB positive control
Human brain glioma tissue
WB Predicted band size
50
ELISA Recommended dilution
500-5000
Gene Accssion
BC000748
Synonyms
TUBB4
Full name
Tubulin beta-3 chain
Content(mg/ml)
0.5
Immunogen
Fusion protein corresponding to a region derived from 57-294 amino acids of Human Tubulin beta-3 chain